http://www.freshpatents.com/Chemistry--molecular-biology-and-microbiology-dtnewntc435.php USPTO Class 435 - Chemistry: molecular biology and microbiology en-us Wed, 30 Apr 2008 12:34:54 -0700 1000 Wednesday Thursday Friday Saturday Sunday 141 31 http://www.freshpatents.com/index.php?rss=true http://www.freshpatents.com/images/freshpatentsnav_rss.gif http://www.freshpatents.com/Method-to-predict-degradation-of-a-landfill-dt20080424ptan20080096188.php Wed, 30 Apr 2008 12:34:54 -0700 Determining when a landfill is stabilized by comparing the biological signature of a landfill over a predetermined time period with that of a known stabilized landfill.... http://www.freshpatents.com/Pcr-primer-set-for-detecting-severe-acute-respiratory-syndrome--sars--coronavirus-method-and-kit-for-detecting-sars-coronavirus-using-the-same-dt20080424ptan20080096186.php Wed, 30 Apr 2008 12:34:54 -0700 Provided are SARS-CoV detection PCR primers having nucleotide sequences as set forth in SEQ ID NOS: 1-46, a method for detecting SARS-CoV using the primers, and a SARS-CoV detection kit including the primers.... http://www.freshpatents.com/Method-for-analyzing-samples-by-means-of-hybridization-dt20080424ptan20080096196.php Wed, 30 Apr 2008 12:34:54 -0700 The invention is distinguished by the fact that the target molecules have a detectable marking in proximity to a target sequence and/or a detectable marking is incorporated in the target sequence. By this means, significantly higher signal intensities are obtained than with conventional methods. The invention relates to a method of... http://www.freshpatents.com/Method-for-de-novo-detection-of-sequences-in-nucleic-acids--target-sequencing-by-fragmentation-dt20080424ptan20080096194.php Wed, 30 Apr 2008 12:34:54 -0700 The present invention provides a method for determining nucleic acid sequences of a template nucleic acid that requires no prior knowledge of the nucleic acid sequence present in the template nucleic acid. The method is based on combining information about the mass of a fragment, the mass of any one... http://www.freshpatents.com/Methods-and-compositions-for-detecting-polynucleotides-dt20080424ptan20080096193.php Wed, 30 Apr 2008 12:34:54 -0700 Methods of determining the presence or amount of a target polynucleotide in a sample are provided. A sample that contains a target polynucleotide, a nucleic acid analog that is complementary to a target nucleic acid sequence of the target polynucleotide, and a dye for which the rate of change in... http://www.freshpatents.com/Nucleic-acid-amplification-assay-and-arrangement-therefor-dt20080424ptan20080096192.php Wed, 30 Apr 2008 12:34:54 -0700 A nucleic acid amplification assay for quantitative and/or qualitative analysis of the presence of a specific analyte or specific analytes in a biological sample, which analytes, if present, are contained in particles (4) of the sample (2), in which assay the sample is forced in a first direction through a... http://www.freshpatents.com/Salmonella-selective-enrichment-medium-containing-tetrathionate-and-magnesium-salt-dt20080424ptan20080096195.php Wed, 30 Apr 2008 12:34:54 -0700 The invention relates to a salmonella selective enrichment medium containing tetrathionate or a salt thereof and at least one type of magnesium salt and to a method for detecting salmonella in a sample by using said selective enrichment medium.... http://www.freshpatents.com/Biological-molecule-immobilized-chip-and-its-use-dt20080424ptan20080096219.php Wed, 30 Apr 2008 12:34:54 -0700 allowing a biological molecule having a portion capable of forming coordination bond to a metal ion to form a coordination bond to a metal ion, bringing the resultant complex adjacent to an electrically conductive support, and applying reduction potential to the electrically conductive support. A biological molecule-immobilized chip is produced by:... http://www.freshpatents.com/Novel-triazine-based-detoxification-agents-and-their-use-dt20080424ptan20080096220.php Wed, 30 Apr 2008 12:34:54 -0700 wherein one X is N and the other X is N, CCL or CCn; A1 and A2 are each independently O, S or N-R1 and R1 is H, C1-6 alkyl, C1-6 hydroxyalkyl, benzyl or β-phenylethyl; B1 and B2 are each independently an optionally substituted hydrocarbon linkage containing from 1 to... http://www.freshpatents.com/Methods-for-the-detection-and-diagnosis-of-trypanosoma-cruzi-infection-dt20080424ptan20080096232.php Wed, 30 Apr 2008 12:34:54 -0700 The present invention relates to the diagnosis of Trypanosoma cruzi infection.... http://www.freshpatents.com/Isolation-of-immune-complexes-dt20080424ptan20080096233.php Wed, 30 Apr 2008 12:34:54 -0700 The present invention provides methods of detecting and/or isolating immune complexes. The antigen in the immune complexes can further be isolated from the immune complexes to facilitate research and characterization of the antigen. Other embodiments of the present invention can be used to, inter alia, develop assays for detecting immune... http://www.freshpatents.com/Method-of-detecting-drug-resistant-microorganisms-by-surface-plasmon-resonance-system-dt20080424ptan20080096241.php Wed, 30 Apr 2008 12:34:54 -0700 The present invention relates to a method and a device for detecting a drug resistant microorganism by surface plasmon resonance (SPR).... http://www.freshpatents.com/Cystatin-based-peptide-tags-for-the-expression-and-purification-of-bioactive-peptides-dt20080424ptan20080096245.php Wed, 30 Apr 2008 12:34:54 -0700 Cystatin-based peptide tags, referred to here as inclusion body tags (IBTs), are disclosed useful for the generation of insoluble fusion peptides. The fusion peptides comprise at least one inclusion body tag operably linked to a peptide of interest. Expression of the fusion peptide in a host cell results in a... http://www.freshpatents.com/Zein-based-peptide-tags-for-the-expression-and-purification-of-bioactive-peptides-dt20080424ptan20080096246.php Wed, 30 Apr 2008 12:34:54 -0700 Zein-based peptide tags, referred to here as inclusion body tags (IBTs), are disclosed useful for the generation of insoluble fusion peptides. The fusion peptides comprise at least one inclusion body tag operably linked to a peptide of interest. Expression of the fusion peptide in a host cell results in a... http://www.freshpatents.com/Production-and-purification-of-il-29-dt20080424ptan20080096252.php Wed, 30 Apr 2008 12:34:54 -0700 The expression vectors and methods using an E. Coli expression system for the large scale production of IL-29 are described. The vectors utilize the IL-29 coding sequence with specific changes in nucleotides in order to optimize codons and mRNA secondary structure for translation in E. coli. Also included are methods... http://www.freshpatents.com/Method-for-preparing-sequence-tags-dt20080424ptan20080096255.php Wed, 30 Apr 2008 12:34:54 -0700 Means to circulate any nucleic acid molecule and to obtain from such circular nucleic acid molecules fragments that mark both ends of the initial nucleic acid molecule are provided. Means of high value to studies including, but not limited to, expression profiling, splicing, promoter identification, identification of genetic elements, and... http://www.freshpatents.com/System-for-exsanguinous-metabolic-support-of-an-organ-or-tissue-dt20080424ptan20080096184.php Wed, 30 Apr 2008 12:34:54 -0700 An exsanguinous metabolic support system for maintaining an organ or tissue at a near normal metabolic rate is disclosed that employs a warm perfusion solution capable of altering the production of nitric oxide (NO) in an organ or tissue and supporting the metabolism of the organ or tissue at normothermic... http://www.freshpatents.com/Method-for-eliminating-potentially-toxic-and-or-harmful-substances-dt20080424ptan20080096185.php Wed, 30 Apr 2008 12:34:54 -0700 The invention describes a method for eliminating potentially toxic and/or harmful substances, wherein particles which are capable of binding, taking up and/or carrying the toxic and/or harmful substances, are removed from a body fluid in an extracorporeal step or in an extrinsic or exogeneous device.... http://www.freshpatents.com/Device-and-method-for-detection-of-analytes-dt20080424ptan20080096189.php Wed, 30 Apr 2008 12:34:54 -0700 The present invention provides assays and devices for detection of substances in liquid samples. The assays and devices utilize passive diffusion between a porous material and a porous membrane containing a specific binding pair member to enable detection of the substance of interest.... http://www.freshpatents.com/Methods-and-systems-for-detection-and-isolation-of-a-nucleotide-sequence-dt20080424ptan20080096191.php Wed, 30 Apr 2008 12:34:54 -0700 A method for isolating nucleic acid molecules having a repeating nucleotide sequence or a homopolymeric nucleotide sequence, e.g. a poly A stretch, is described. In particular, the method uses oligomeric capture probes spiked with various amounts of locked nucleic acid (LNA). The invention further describes methods for the isolation of... http://www.freshpatents.com/Molecular-scaffolds-for-hiv-1-epitopes-dt20080424ptan20080096187.php Wed, 30 Apr 2008 12:34:54 -0700 Methods and compositions are provided for the use of an envelope polypeptide or a functional variant thereof from a lentivirus that is not HIV-1 as a molecular scaffold for HIV-1 epitopes. The HIV-1 epitopes can be recognized by HIV-1 binding antibodies, HIV-1 neutralizing antibodies and/or CD4-induced antibodies. Thus, methods are... http://www.freshpatents.com/Sequences-diagnostic-for-shrimp-pathogens-dt20080424ptan20080096190.php Wed, 30 Apr 2008 12:34:54 -0700 Primers have been isolated that are diagnostic for the detection of the white spot syndrome virus (WSSV). The primers are based on a new portion of the WSSV genome and may be used in primer directed amplification or nucleic acid hybridization assay methods.... http://www.freshpatents.com/Analysis-of-hiv-1-coreceptor-use-in-the-clinical-care-of-hiv-1-infected-patients-dt20080424ptan20080096209.php Wed, 30 Apr 2008 12:34:54 -0700 A change in viral tropism occurs in many HIV positive individuals over time and can be indicated by a change in coreceptor usage from CCR5 to CXCR4. The change in coreceptor usage to CXCR4 has been shown to correlate with increased disease progression. In patients undergoing HAART, the predominant populations... http://www.freshpatents.com/Animal-models-for-demyelination-disorders-dt20080424ptan20080096202.php Wed, 30 Apr 2008 12:34:54 -0700 This invention is in the field of neurology. Specifically, the invention relates to the discovery and characterization of molecular components that play a role in neuronal demyelination or remyelination. In addition, the invention relates to the generation of an animal model that exhibits hypomyelination. The compositions and methods embodied in... http://www.freshpatents.com/Assay-for-identifying-biological-targets-of-polynucleotide-binding-compounds-dt20080424ptan20080096201.php Wed, 30 Apr 2008 12:34:54 -0700 The present invention provides methods and systems for the identification of a biological target of a chemical compound, such as saframycin A, known to bind a polynucleotide. The invention also provides methods of screening chemical compounds for those which act in a similar method and may be more potent than... http://www.freshpatents.com/Biomarkers-for-assessing-response-to-c-met-treatment-dt20080424ptan20080096208.php Wed, 30 Apr 2008 12:34:54 -0700 Biomarkers that correlate to treatment with drugs that inhibit c-met are disclosed. These biomarkers have been shown to have utility in assessing response to the compounds. The expression level of the biomarkers is reduced upon treatment with c-met inhibitor compounds, thus indicating that these biomarkers are involved in c-met activity.... http://www.freshpatents.com/Cancer-suppressing-agent-dt20080424ptan20080096210.php Wed, 30 Apr 2008 12:34:54 -0700 An object of the present invention is to provide a cancer suppressing agent containing a cancer suppressing gene that is discovered through the use of a novel method rather than through existing methods. The present invention provides a cancer suppressing agent which comprises an RGC32 gene or a gene homologous... http://www.freshpatents.com/Compositions-and-methods-for-the-diagnosis-and-treatment-of-tumor-dt20080424ptan20080096215.php Wed, 30 Apr 2008 12:34:54 -0700 The present invention is directed to compositions of matter useful for the diagnosis and treatment of tumor in mammals and to methods of using those compositions of matter for the same.... http://www.freshpatents.com/Compounds-and-methods-for-assessment-of-microsatellite-instability--msi--status-dt20080424ptan20080096197.php Wed, 30 Apr 2008 12:34:54 -0700 The present invention provides a method for assessment of the Microsatellite Instability (MSI) status of medically relevant conditions associated with MSI phenotype such as e.g. neoplastic lesions. The method is based on the analysis of a monomorphic T25 (CAT25) mononucleotide repeat located in the 3′-UTR of the Caspase 2 (CASP2)... http://www.freshpatents.com/Corynebacterium-glutamicum-genes-encoding-proteins-involved-in-genetic-stability-gene-expression-and-protein-secretion-and-folding-dt20080424ptan20080096211.php Wed, 30 Apr 2008 12:34:54 -0700 Isolated nucleic acid molecules, designated SES nucleic acid molecules, which encode novel SES proteins from Corynebacterium glutamicum are described. The invention also provides antisense nucleic acid molecules, recombinant expression vectors containing SES nucleic acid molecules, and host cells into which the expression vectors have been introduced. The invention still further... http://www.freshpatents.com/Diagnostic-methods-and-kits-for-colorectal-cancer-dt20080424ptan20080096205.php Wed, 30 Apr 2008 12:34:54 -0700 The present application discloses a diagnostic method and a kit for prognosis assessment of colorectal cancer (CRC) and a novel tumor suppressor gene to be used for diagnosis of colorectal cancer (CRC), the method comprising the steps of: (a) identifying recurrently altered regions (RAR) on a chromosome; and (b) detecting... http://www.freshpatents.com/Leptin-and-growth-hormone-receptor-gene-markers-associated-with-rearing-carcass-traits-and-productive-life-in-cattle-dt20080424ptan20080096207.php Wed, 30 Apr 2008 12:34:54 -0700 The invention provides a method for sub-grouping animals according to genotype wherein the animals of each sub-group have a similar polymorphism or combination of polymorphisms in the leptin gene selected from the group consisting of UASMS1, UASMS2, UASMS3, EXON2-FB, and E2JW. The combination of single nucleotide polymorphisms of the leptin... http://www.freshpatents.com/Method-and-apparatus-for-determining-cancer-metastasis-dt20080424ptan20080096204.php Wed, 30 Apr 2008 12:34:54 -0700 A method which can objectively determine to what extent a cancer cell has metastasized to a lymph node, the method being a method for determining a size of a metastatic focus, including a step of quantitating a tumor marker mRNA in an assay sample prepared from a lymph node suspected... http://www.freshpatents.com/Method-and-device-for-detecting-quinolone-resistant-escherichia-coli-dt20080424ptan20080096203.php Wed, 30 Apr 2008 12:34:54 -0700 The present invention pertains to a method for detecting quinolone-resistant Escherichia coli strains in a biological sample. The present invention also relates to a kit adapted to perform the inventive method.... http://www.freshpatents.com/Method-for-agitating-the-fluid-contents-of-a-container-dt20080424ptan20080096214.php Wed, 30 Apr 2008 12:34:54 -0700 An automated analyzer for performing multiple diagnostic assays simultaneously includes multiple stations, or modules, in which discrete aspects of the assay are performed on fluid samples contained in reaction receptacles. The analyzer includes stations for automatically preparing a specimen sample, incubating the sample at prescribed temperatures for prescribed periods, performing... http://www.freshpatents.com/Method-for-confirming-conversion-treatment-and-nucleic-acid-molecule-used-therefor-dt20080424ptan20080096213.php Wed, 30 Apr 2008 12:34:54 -0700 There is provided a method for confirming conversion treatment of non-methylated cytosine, including a step of mixing a DNA taken from a living body, with a nucleic acid for accuracy control having a sequence A which is not contained in a genome of the living body and contains cytosine, a... http://www.freshpatents.com/Method-for-the-carry-over-protection-in-dna-amplification-systems-targeting-methylation-analysis-achieved-by-a-modified-pre-treatment-of-nucleic-acids-dt20080424ptan20080096199.php Wed, 30 Apr 2008 12:34:54 -0700 Disclosed is a method for the specific amplification of template DNA in the presence of potentially contaminating PCR products from previous amplification experiments. In the first step DNA is contacted with a bisulfite solution, which reacts with unmethylated cytosines but not with methylated cytosines, by sulfonating them. This results in... http://www.freshpatents.com/Method-to-determine-responsiveness-of-cancer-to-epidermal-growth-factor-receptor-targeting-treatments-dt20080424ptan20080096212.php Wed, 30 Apr 2008 12:34:54 -0700 The present invention is directed to a method for determining the responsiveness of cancer to an epidermal growth factor receptor (EGFR) treatment. In a preferred embodiment, the presence of at least one variance in the kinase domain of the erbB1 gene confers sensitivity to the tyrosine kinase inhibitor gefitinib. Thus,... http://www.freshpatents.com/Methods-and-apparatuses-for-analyzing-polynucleotide-sequences-dt20080424ptan20080096216.php Wed, 30 Apr 2008 12:34:54 -0700 Methods for high speed, high throughput analysis of polynucleotide sequences, and apparatuses with which to carry out the methods are provided in the invention.... http://www.freshpatents.com/Methods-for-detection-of-a-target-nucleic-acid-by-capture-using-multi-subunit-probes-dt20080424ptan20080096200.php Wed, 30 Apr 2008 12:34:54 -0700 The invention relates to generating a signal indicative of a target nucleic acid sequence, comprising forming a complex by incubating a sample comprising a target nucleic acid sequence with a probe comprising a first and second subunit, and a binding moiety, and dissociating the first and second subunit to release... http://www.freshpatents.com/Methods-for-evaluating-pathologic-conditions-using-extracellular-rna-dt20080424ptan20080096217.php Wed, 30 Apr 2008 12:34:54 -0700 This invention provides methods for the detection, diagnosing, monitoring, or predicting of non-neoplastic diseases, pathologic conditions, and injury. The methods of the invention detect extracellular non-neoplastic mammalian RNA in the blood, blood plasma, serum, or other bodily fluid of an animal, most preferably a human, having or predisposed to having... http://www.freshpatents.com/Polynucleotide-encoding-a-maize-herbicide-resistance-gene-and-methods-for-use-dt20080424ptan20080096218.php Wed, 30 Apr 2008 12:34:54 -0700 This invention relates to polynucleotide sequences encoding a gene that can confer resistance to at least one herbicide. It further relates to plants and seeds of plants carrying chimeric genes comprising said polynucleotide sequences, which enhance or confer resistance to at least one herbicide, and methods of making said plants... http://www.freshpatents.com/Polynucleotide-sequencing-using-a-helicase-dt20080424ptan20080096206.php Wed, 30 Apr 2008 12:34:54 -0700 The present invention pertains to a method for sequencing a polynucleotide, comprising the steps of: (i) reacting a target polynucleotide with a helicase/primase enzyme (which may be immobilised), under conditions suitable for enzyme activity; and (ii) detecting the interaction between the enzyme and a nucleotide on the target, by measuring... http://www.freshpatents.com/Primer-having-promoter-region-added-thereto-dt20080424ptan20080096198.php Wed, 30 Apr 2008 12:34:54 -0700 It is intended to provide a primer having a promoter region added thereto; and a method of using the primer having a promoter region added thereto in RNA amplification, gene expression analysis and/or identification analysis of an organism. A primer is constructed by adding a promoter region to a random... http://www.freshpatents.com/Assays-for-detecting-modulators-of-cytoskeletal-function-dt20080424ptan20080096225.php Wed, 30 Apr 2008 12:34:54 -0700 Described herein are methods of identifying compounds which modulate the activity of the cytoskeletal system. The methods are rapid, convenient and sensitive. Preferably, the method is used to identify lead compounds that can be used as therapeutics, diagnostics and agricultural agents. Generally, test compounds are added to two cytoskeletal components... http://www.freshpatents.com/Compositions-and-methods-based-upon-the-kinase-haspin-dt20080424ptan20080096222.php Wed, 30 Apr 2008 12:34:54 -0700 The present invention is directed to methods for increasing or decreasing the phosphorylation of histone H3 using factors that alter the activity of the kinase haspin. The invention includes assays for identifying inhibitors, peptides that can serve as inhibitors or in the generation of antibodies that specifically recognize phosphorylated histone,... http://www.freshpatents.com/Emission-ratiometric-indicators-of-phosphoinositides-dt20080424ptan20080096224.php Wed, 30 Apr 2008 12:34:54 -0700 Emission ratiometric indicators of phosphoinositides comprise a fusion protein comprising a pleckstrin homology (PH) domain of Akt (also known as protein kinase B) and a “pseudoligand” containing acidic amino acid residues, which is sandwiched between resonance energy transfer (RET) pairs, such as cyan and yellow mutants of GFP (a FRET... http://www.freshpatents.com/Method-for-predicting-responsiveness-of-breast-cancer-to-antiestrogen-therapy-dt20080424ptan20080096226.php Wed, 30 Apr 2008 12:34:54 -0700 The invention is directed to diagnostic and monitoring methods (assays) for cancer and kits that may be used in such methods. More particularly, an aspect of the invention relates to the use of activated Stat5 for diagnosing and monitoring breast cancer and predicting the effectiveness of cancer treatment. The invention... http://www.freshpatents.com/Method-of-detecting-platelet-thrombosis-or-organ-failure-dt20080424ptan20080096221.php Wed, 30 Apr 2008 12:34:54 -0700 A method of detecting platelet thrombosis or organ failure in a patient suffering from disseminated intravascular coagulation (DIC) or systemic inflammatory response syndrome (SIRS), comprising analyzing a von Willebrand factor-cleaving protease and/or a cleaving factor thereof, is disclosed. A kit for detecting platelet thrombosis or organ failure in a patient... http://www.freshpatents.com/Methods-and-assays-for-distinguishing-between-different-forms-of-diseases-and-disorders-characterized-by-thrombocytopenia-and-or-by-spontaneous-interaction-between-von-willebrand-factor--vwf--and-platelets-dt20080424ptan20080096223.php Wed, 30 Apr 2008 12:34:54 -0700 The invention relates to a method for distinguishing between different states or forms of diseases and disorders characterized by thrombocytopenia and/or by spontaneous interaction between Von Willebrand Factor (vWF) and platelets, and/or to predict the progression of such a disease or disorder, said method comprising the steps of providing at... http://www.freshpatents.com/Crac-modulators-and-use-of-same-for-drug-discovery-dt20080424ptan20080096227.php Wed, 30 Apr 2008 12:34:54 -0700 The invention relates to use of a calcium release activated Ca+2 (CRAC) channel (CRACM) such as CRACM1 and CRACM2 to identify bioactive agents which can modulate store operated calcium entry and CRAC channel activity. The invention further relates to the use of recombinant nucleic acids that encode CRACM. One aspect... http://www.freshpatents.com/Simultaneous-assay-of-target-and-target-drug-binding-dt20080424ptan20080096231.php Wed, 30 Apr 2008 12:34:54 -0700 Whole cell, simultaneous target and drug-target assay using differentially labeled antibodies and flow cytometry. First antibody binds to total target and second antibody binds to the drug binding site of the target, thus drug binding will competitively inhibit the second antibody allowing for a competitive inhibition assay of drug-target binding.... http://www.freshpatents.com/Biomarkers-for-cancer-sensitivity-and-uses-thereof-dt20080424ptan20080096235.php Wed, 30 Apr 2008 12:34:54 -0700 Disclosed herein are biomarkers and uses thereof for evaluating anti-cancer efficacy and sensitivity.... http://www.freshpatents.com/Method-for-examining-carcinoma-and-adenoma-dt20080424ptan20080096234.php Wed, 30 Apr 2008 12:34:54 -0700 [MEANS FOR SOLVING PROBLEMS] Significant differences in the distribution of GlcNAc-6-sulfotransferase isozymes, sulfation enzymes of sugar residues, between non-carcinoma tissues and carcinoma tissues or adenoma tissues were discovered. The discovery is evidently applicable to detect carcinomas and adenomas (except colorectal carcinomas and colorectal adenomas) specifically by assaying a certain range... http://www.freshpatents.com/Method-for-detecting-the-presence-of-target-bacteria-or-a-target-component-carbohydrate-antigen-thereof-dt20080424ptan20080096236.php Wed, 30 Apr 2008 12:34:54 -0700 A process is disclosed for separating a carbohydrate antigen from a Gram-positive or Gram-negative bacteria in a purified form that contains no more than 10% protein. The separated antigen is coupled to an affinity column, over which polyclonal antibodies to the same bacteria are chromatographed and recovered in a purified... http://www.freshpatents.com/Compositions-and-methods-relating-to-mammalian-internal-ribosome-entry-sites-dt20080424ptan20080096228.php Wed, 30 Apr 2008 12:34:54 -0700 Contemplated compositions and methods are directed to IRES sequences and their use, especially in the context of CML. Among other contemplated aspects IRES sequences described herein are highly active in recombinant in vitro systems and allow high-level of recombinant protein from two, typically opposite reading frames. In vivo, and particularly... http://www.freshpatents.com/Methods-for-assaying-percentage-of-glycated-hemoglobin-dt20080424ptan20080096230.php Wed, 30 Apr 2008 12:34:54 -0700 The invention provides enzymatic methods for direct determination of percentage of glycated hemoglobin in blood samples without the need of a separated measurement of total hemoglobin content in blood samples. The methods utilizes one or two different types of oxidizing agents which selectively oxidize low-molecular weight reducing substances and high-molecular... http://www.freshpatents.com/Modified-flagellins-and-flagellar-filaments-useful-as-receptors-and-methods-for-the-preparation-thereof-dt20080424ptan20080096229.php Wed, 30 Apr 2008 12:34:54 -0700 In general, the invention relates to receptors capable of the efficient recognition and binding of target molecules, said receptors being composed of flagellin proteins which comprise the flagellar filaments of bacteria. More closely, the invention relates to modified flagellins or flagellin fragments useful as receptors, and filamentous receptor-structures comprising them.... http://www.freshpatents.com/High-throughput-assay-for-human-rho-kinase-activity-with-enhanced-signal-to-noise-ratio-dt20080424ptan20080096238.php Wed, 30 Apr 2008 12:34:54 -0700 The present invention provides a high throughput assay with increased signal-to-noise ration for human Rho kinase activity in vitro, and methods and kits therefor. A high throughput method of assaying a test compound for human Rho kinase modulating activity is also provided.... http://www.freshpatents.com/Method-for-identifying-agents-which-modulate-cell-growth-or-survival-dt20080424ptan20080096237.php Wed, 30 Apr 2008 12:34:54 -0700 The present invention relates to a method for identifying an agent, for modulating cell growth or survival. The method involves the identification of an agent which modulates the net ratio of nuclear-localized versus cytosolic-localized H11 kinase or mutant H11 kinase in a cell. A method for diagnosing a cancer associated... http://www.freshpatents.com/Novel-prostamide-receptor-antagonists-dt20080424ptan20080096240.php Wed, 30 Apr 2008 12:34:54 -0700 wherein A, R1, R2, R3, R4 and R6 are as defined in the specification. The present invention provides prostamide receptor antagonist compounds that may be represented by the general formula I.... http://www.freshpatents.com/Orphan-nuclear-receptor-dt20080424ptan20080096239.php Wed, 30 Apr 2008 12:34:54 -0700 The present invention relates to a novel human orphan nuclear receptor that binds to a cytochrome P-450 monoxygenase (CYP) promoter and that is activated by compounds that induce CYP gene expression. The invention further relates to nucleic acid sequences encoding such a receptor, to methods of making the receptor and... http://www.freshpatents.com/Enhanced-substrate-conversion-efficiency-of-fermentation-processes-dt20080424ptan20080096242.php Wed, 30 Apr 2008 12:34:54 -0700 The present invention relates to the field of fermentation technology. In particular the invention relates to fermentation processes for the production of a first and a second fermentation product by a single production organism wherein the first product is in a more reduced state than the substrate and the second... http://www.freshpatents.com/Soy-protein-isolate-and-process-for-its-manufacture-dt20080424ptan20080096243.php Wed, 30 Apr 2008 12:34:54 -0700 A soy protein isolate and method for preparing the same are disclosed. The novel soy protein isolate possesses excellent suspension stability and flavor. The process used to produce the soy protein isolate includes an enzyme hydrolysis process, and the resulting soy protein isolate can be used in acidic beverage formulations.... http://www.freshpatents.com/Agarase-and-gene-thereof-dt20080424ptan20080096249.php Wed, 30 Apr 2008 12:34:54 -0700 Production of efficiently producing agaro-oligosaccharide; a polypeptide having an agarase activity which is usable in, for example, efficiently extracting a substance such as a nucleic acid from an agarose gel; the amino acid sequence of the polypeptide; a gene encoding the polypeptide; a process for producing the polypeptide; a process... http://www.freshpatents.com/D-aminoacylase-dt20080424ptan20080096244.php Wed, 30 Apr 2008 12:34:54 -0700 A D-aminoacylase produced by a microorganism of genus Defluvibacter; which acts on a N-acetyl-D-amino acid; which has a molecular weight (as determined by electrophoresis) of about 55,000 daltons, and an isoelectric point (as determined by two-dimensional electrophoresis for denatured system) of 5.3; which acts on N-acetyl-D-valine, N-acetyl-D-leucine, and the like,... http://www.freshpatents.com/Modified-clostridial-toxins-with-enhanced-targeting-capabilities-for-endogenous-clostridial-toxin-receptor-systems-dt20080424ptan20080096248.php Wed, 30 Apr 2008 12:34:54 -0700 The specification discloses modified Clostridial toxins comprising a Clostridial toxin enzymatic domain, a Clostridial toxin translocation domain and an enhanced Clostridial toxin binding domain; polynucleotide molecules encoding such modified Clostridial toxins; and method of producing such modified Clostridial toxins.... http://www.freshpatents.com/Nucleic-acids-encoding-duramycin-dt20080424ptan20080096247.php Wed, 30 Apr 2008 12:34:54 -0700 Nucleic acids encoding preduramycin and produramycin are described, along with recombinant nucleic acids host cells containing the same and methods of use thereof, such as for the manufacture of the lantibiotic duramycin.... http://www.freshpatents.com/Toll-interleukin-1-receptor-adapter-protein--tirap--dt20080424ptan20080096250.php Wed, 30 Apr 2008 12:34:54 -0700 TIRAP polypeptides and polynucleotides and methods for producing such polypeptides by recombinant techniques are disclosed. Also disclosed are methods for utilizing TIRAP polypeptides and polynucleotides in therapy, and diagnostic assays for such.... http://www.freshpatents.com/Invertebrate-derived-gonadotropic-hormone-and-its-synthesis-dt20080424ptan20080096251.php Wed, 30 Apr 2008 12:34:54 -0700 The structure of gonadotropic hormone of an invertebrate (Asterina pectinifera) was elucidated. The gonadotropic hormone is a peptide with molecular weight 4500 to 4900 composed of two subunits, wherein the structure of the protein has the structure bound by SS bridges formed between SH residues of cysteines contained in the... http://www.freshpatents.com/Methods-of-making-nanotechnological-and-macromolecular-biomimetic-structures-dt20080424ptan20080096253.php Wed, 30 Apr 2008 12:34:54 -0700 The present invention is in the fields of nanotechology and biomimetics. In particular, the present invention relates to the use of modified ribosomes to produce biomimetic structures. These biomimetic structures, also known as directed element polymers, are not produced by traditional industrial means but instead are produced by living systems... http://www.freshpatents.com/Process-for-producing-alpha14-galactosyltransferase-and-galactose-containing-complex-carbohydrate-dt20080424ptan20080096254.php Wed, 30 Apr 2008 12:34:54 -0700 The present invention can provide a process for producing a protein having α1.4-galactosyltransferase activity using a transformant comprising a DNA encoding a protein having α1.4-galactosyltransferase activity derived from a microorganism belonging to the genus Pasteurella and a process for producing a galactose-containing complex carbohydrate using a transformant capable of producing... http://www.freshpatents.com/Method-for-gene-expression-dt20080424ptan20080096256.php Wed, 30 Apr 2008 12:34:54 -0700 The invention relates to a method for gene expression in a cell-free translation system, wherein the reaction solution comprises an RNA matrix with a gene sequence, which codes for an expression product to be expressed, and a translation system from eukaryotic cells, wherein the reaction solution is incubated, and wherein... http://www.freshpatents.com/Methods-for-rapid-single-step-strand-displacement-amplification-of-nucleic-acids-dt20080424ptan20080096257.php Wed, 30 Apr 2008 12:34:54 -0700 A single-step, isothermal strand displacement amplification method that is conducted without the requirement for heat denaturation of the target nucleic acid. The method is particularly useful for analysis of clinical samples due to the decreased risk of potential contamination of the patient sample.... http://www.freshpatents.com/Rolling-circle-amplification-of-circular-genomes-dt20080424ptan20080096258.php Wed, 30 Apr 2008 12:34:54 -0700 Disclosed are compositions and a method for amplification of circular genomes. The method is based on rolling circle amplification of the circular genomes which involves strand displacement replication by primers. The disclosed method allows differential amplification of circular genomes of interest. In genomic nucleic acid samples containing both a circular... http://www.freshpatents.com/Method-of-aminoacylating-trna-dt20080424ptan20080096259.php Wed, 30 Apr 2008 12:34:54 -0700 It is intended to provide a method of chemically synthesizing an aminoacyl tRNA which is completely different from the existing methods, namely, a highly efficient and practically usable method for synthesizing an aminoacyl tRNA whereby any nonnatural amino acid can be conveniently aminoacylated without a need for genetic engineering techniques... http://www.freshpatents.com/Method-of-preparing-a-heat-treated-product-dt20080424ptan20080096260.php Wed, 30 Apr 2008 12:34:54 -0700 The formation of acrylamide during heat treatment in the production of a food product is reduced by treating the raw material with an enzyme before the heat treatment. The enzyme is capable of reacting on asparagine as a substrate.... http://www.freshpatents.com/Alcohol-production-using-sonication-dt20080424ptan20080096261.php Wed, 30 Apr 2008 12:34:54 -0700 A system comprising one or more transducers and an alcohol production facility having a liquid medium processing stream, the alcohol production facility adapted for use with the one or more transducers is provided. In one embodiment, the one or more transducers apply sonication to the liquid medium processing stream in... http://www.freshpatents.com/Method-for-enhancing-polymerase-activity-dt20080424ptan20080096262.php Wed, 30 Apr 2008 12:34:54 -0700 A polymerase activity is effectively enhanced by adding an anionic surfactant, in particular an anionic surfactant having a polyethoxyl group, to a reaction mixture containing a polymerase.... http://www.freshpatents.com/Attenuated-parainfluenza-virus--piv--vaccines-dt20080424ptan20080096264.php Wed, 30 Apr 2008 12:34:54 -0700 The invention provides isolated nucleic acids encoding recombinant genomes or antigenomes of Human Parainfluenza Viruses that are useful as vaccines. The recombinant genomes or antigenomes can be incorporated into expression vectors for production of recombinant viruses in vitro. The invention also provides recombinant Human Parainfluenza viruses having one or more... http://www.freshpatents.com/Recombinant-parainfluenza-virus-expression-systems-and-vaccines-comprising-heterologous-antigens-derived-from-respiratory-syncytial-virus-dt20080424ptan20080096263.php Wed, 30 Apr 2008 12:34:54 -0700 The present invention relates to recombinant bovine parainfluenza virus (bPIV) cDNA or RNA which may be used to express heterologous gene products in appropriate host cell systems and/or to rescue negative strand RNA recombinant viruses that express, package, and/or present the heterologous gene product. In particular, the heterologous gene products... http://www.freshpatents.com/Culture-medium-for-the-production-of-filamentary-fungi-dt20080424ptan20080096265.php Wed, 30 Apr 2008 12:34:54 -0700 A culture medium for filamentary fungi comprising at least one carbon source chosen from the group consisting of molasses, malt extract and sucrose a nd at least one organic nitrogen source chosen from yeast extract and corn steep liquor is described; a method for producing filamentary fungi, in particular nematophagus... http://www.freshpatents.com/Method-for-stabilizing-the-antiallergic-activity-of-lactic-acid-bacteria-against-high-temperature-treatment-stabilized-compositons-and-food-and-drink-dt20080424ptan20080096266.php Wed, 30 Apr 2008 12:34:54 -0700 The present invention provides a method for stabilizing an antiallergic activity of lactic acid bacteria against a high-temperature treatment and a composition for the stabilization, which can maintain an antiallergic activity of lactic acid bacteria against a high-temperature treatment, and foods and drinks such as drinks having a stabilized antiallergic... http://www.freshpatents.com/Systems-and-methods-for-large-scale-production-and-harvesting-of-oil-rich-algae-dt20080424ptan20080096267.php Wed, 30 Apr 2008 12:34:54 -0700 Systems and methods for the growing of microorganisms such as algae, yeast, and bacteria are described. Seed fermentation units are associated with final fermentation ponds in various arrangements. Continuous, semicontinuous, fed batch, and batch modes of operation of the seed and final fermentations are included. Harvest methods for the cellular... http://www.freshpatents.com/Biotrickling-filter-packing-material-and-systems-and-methods-of-using-same-to-remove-odour-causing-compounds-from-waste-gas-streams-dt20080424ptan20080096268.php Wed, 30 Apr 2008 12:34:54 -0700 The present invention relates to biotrickling filter systems and the packing material employed in such systems, as well as, methods of using same to remove odour causing compounds from waste gas streams. The packing material for the biotrickling filter system includes a plurality of expanded glass granules. When used in... http://www.freshpatents.com/Plate-and-method-for-high-throughput-screening-dt20080424ptan20080096269.php Wed, 30 Apr 2008 12:34:54 -0700 A multiple well plate and method for media exchange, including a body defining a plurality of cell wells each connected via a channel to one of a plurality of aspiration holes, is provided. The cell wells contain a porous, hydrophilic frit which is suspended on a ledge above a reservoir... http://www.freshpatents.com/Plate-and-method-for-high-throughput-screening-dt20080424ptan20080096270.php Wed, 30 Apr 2008 12:34:54 -0700 A multiple well plate and method for media exchange, including a body defining a plurality of cell wells each connected via a channel to one of a plurality of aspiration holes, is provided. The cell wells contain a porous, hydrophilic frit which is suspended on a ledge above a reservoir... http://www.freshpatents.com/Polymeric-self-assembly-multiplayer-membranes-for-ion-screening--design-fabrication-and-application-in-sensors-dt20080424ptan20080096271.php Wed, 30 Apr 2008 12:34:54 -0700 The embodiments of the invention are related to an extrinsically compensated multilayer membrane comprising at least a first layer comprising charged polymers and a second layer comprising neutral polymers, wherein the first layer is characteristic of extrinsic compensation and the charges on the polymer are balanced by mobile counter ions.... http://www.freshpatents.com/Plate-and-method-for-high-throughput-screening-dt20080424ptan20080096272.php Wed, 30 Apr 2008 12:34:54 -0700 A multiple well plate and method for media exchange, including a body defining a plurality of cell wells each connected via a channel to one of a plurality of aspiration holes, is provided. The cell wells contain a porous, hydrophilic frit which is suspended on a ledge above a reservoir... http://www.freshpatents.com/Method-for-preparing-conditioned-medium-of-astrocyte-like-cells-dt20080424ptan20080096273.php Wed, 30 Apr 2008 12:34:54 -0700 Disclosed are a method for preparing a conditioned medium of astrocyte-like cells derived from embryonic stem cells, characterized in that astrocyte-like cells, which are prepared by differentiation of embryonic stem cells, are cultured; the medium obtained by said method, the use of the conditioned medium for culturing neural cells as... http://www.freshpatents.com/Recombinant-alphavirus-vectors-and-methods-of-using-same-dt20080424ptan20080096274.php Wed, 30 Apr 2008 12:34:54 -0700 The present invention describes nucleic acid segments, recombinant alphavirus vectors, and recombinant alphavirus particles that include a Sindbis viral vector. The Sindbis viral vector includes a nucleic acid segment encoding a fusion protein comprising a Sindbis virus nonstructural protein and a protein or peptide of interest, wherein the production of... http://www.freshpatents.com/Protein-for-improving-cell-attachment-efficiency-and-use-thereof-dt20080424ptan20080096275.php Wed, 30 Apr 2008 12:34:54 -0700 The present invention provides a method for improving cell-attachment efficiency comprising (a) preparing a protein in aqueous solution, wherein the protein has a formula A-B-C, wherein A represents a GRGDS amino acid sequence; B represents a cellulose binding domain (CBD); and C represents a GRGDS amino acid sequence, an RGD... http://www.freshpatents.com/Cis-prenyltransferases-from-plants-dt20080424ptan20080096276.php Wed, 30 Apr 2008 12:34:54 -0700 This invention pertains to nucleic acid fragments encoding plant proteins that are homologs to the cis-prenyltransferases UPP synthase from the bacterium Micrococcus luteus or Dedol-PP synthase from yeast Saccharomyces cerevisiae. More specifically, this invention pertains to cis-prenyltransferase homologs from wheat, grape, soybean, rice, African daisy, rubber tree latex and pot... http://www.freshpatents.com/Plant-with-reduced-protein-content-in-seed-method-of-constructing-the-same-and-method-of-using-the-same-dt20080424ptan20080096277.php Wed, 30 Apr 2008 12:34:54 -0700 It is intended to provide a method of reducing the total amount of stored protein, to develop a technique required therefor, and to provide a plant and its seeds developed by the above method and a method of using such a plant and seeds. More specifically, a nucleic acid molecule... http://www.freshpatents.com/Rf2a-and-rf2b-transcription-factors-dt20080424ptan20080096278.php Wed, 30 Apr 2008 12:34:54 -0700 A method of activating the rice tungro bacilliform virus (RTBV) promoter in vivo is disclosed. The RTBV promoter is activated by exposure to at least one protein selected from the group consisting of Rf2a and Rf2b.... http://www.freshpatents.com/Nucleic-acid-sequences-encoding-luciferase-for-expression-in-filamentous-fungi-dt20080424ptan20080096279.php Wed, 30 Apr 2008 12:34:54 -0700 The present invention relates to genetic reporters. Specifically, the present invention is directed to a modified gene encoding a luciferase for high level expression in an organism with a bias for cytosine (C) or guanine (G) in the third position of the codon....